- Program
Complete Neuro-Reset
Three consecutive treatments in a single visit — stellate ganglion block with a vagus nerve hydrodissection followed by ketamine therapy — sequenced so the first two treatments creates the conditions for the third to go deeper than it typically can.
- Single visit
- Board-certified psychiatrists
- 281 Broadway, Manhattan
- — The science
You've been doing everything right. Something's still off.
You've been in therapy. You've tried medication — maybe more than once. You exercise, you sleep reasonably well, you've read the books. And yet there's a version of yourself that feels just out of reach. A baseline that should be lower than it is. A sense of clarity you remember having but can't seem to get back to.
That gap isn't a willpower problem. It's often a nervous system problem. When the body has been running in high-alert mode for long enough, no amount of insight or effort fully resolves it — because the alarm is still on at a biological level.
The neuroreset is designed for this situation — not as a replacement for the work you've already done, but as a different kind of approach to what's underneath it.
The Autonmic Nervous System
Sympathetic
Fight-or-flight
- Elevated cortisol & heart rate
- Disrupted sleep & digestion
- Anxiety & hypervigilance
- Immune suppression
- Emotional reactivity
Parasympathetic
Rest & restore
- Regulated heart rate & breathing
- Deep, restorative sleep
- Emotional balance
- Enhanced immune response
- Mental clarity & focus
The Neuro-Reset restores balance between these two systems.
- The Autonomic Nervous System
Sympathetic
Fight-or-flight
- Elevated cortisol & heart rate
- Disrupted sleep & digestion
- Anxiety & hypervigilance
- Immune suppression
- Emotional reactivity
Parasympathetic
Rest & restore
- Regulated heart rate & breathing
- Deep, restorative sleep
- Emotional balance
- Enhanced immune response
- Mental clarity & focus
The Neuro-Reset restores balance between these two systems.
- — Why this, why now
The people who book this have already tried a lot.
The Complete Neuro-Reset isn't a first step. It's what people turn to when they've done the work — the therapy, the medication, the lifestyle changes — and something fundamental still hasn't shifted. It's an intervention at a deeper layer than most treatments reach.
"I've been in therapy for years. I have all the insights. Nothing has actually changed."
"I've tried antidepressants. They helped a little, or not at all, or made things worse."
"I function fine on the outside. Inside I'm exhausted, anxious, and always just managing."
"I went through something significant and I've never quite gotten back to myself."
"I want to feel better — but I don't want another medication or more years of talk therapy."
Ready to make the first step?
- — The protocol
Three treatments.
One session.
One reset.
Most people who've tried ketamine say the Neuro-Reset felt different — quieter, deeper, more like something actually shifted. The reason is the sequence. The stellate ganglion block comes first — not as a separate treatment but as preparation. It creates the conditions that allow the ketamine to reach further than it typically can. Each step makes the next one more effective.
1st Treatment
Stellate Ganglion Block
A precisely targeted injection that temporarily blocks the nerve cluster responsible for maintaining the chronic stress signal. Within minutes, the sympathetic nervous system shifts from its hyperactivated state back toward its pre-stress baseline. Heart rate slows. Cortisol drops. The body remembers what calm feels like.
Most patients describe a noticeable shift within minutes — a physical sense of the tension they've been carrying beginning to ease.
- Duration: 20–30 min
- Method: ultrasound-guided injection, administered by a board-certified physician
- Onset: effects within minutes, followed by a rest period
- Evidence: published research on PTSD, chronic anxiety, and autonomic dysregulation.
2nd Treatment
Vagus Nerve Hydrodissection
The Vagus Nerve Hydrodissection is a minimally-invasive procedure that involves injecting fluid around the Vagus Nerve to release pressure and create space, ultimately improving its function and ability to promote relaxation. Research indicates hydrodissection may also help to alleviate symptoms related to PTSD and anxiety.
A de-compressed Vagus Nerve also facilitates the delivery of substances that can enhance nerve functioning, including exosomes, peptides, platelet plasma, and growth factors.
- After: rest for the remainder of the day
3rd Treatment
IV Ketamine Therapy
With the nervous system no longer locked in fight-or-flight, ketamine can do what it's designed to do. It rapidly stimulates new neural connections, elevates mood, and opens a window of profound neuroplasticity — the same neurological flexibility that makes learning, healing, and perspective shifts possible.
The SGB doesn't just precede the ketamine — it creates the conditions that many patients say allowed the ketamine to land differently than it had before.
- Duration: 60–90 mins
- Method: low-dose infusion, administered with continuous monitoring by our clinical team
- Onset: mood effects often within 24 hours; neuroplasticity window opens during/after
- Evidence: extensive evidence for treatment-resistant depression, PTSD, and acute suicidality
- — What you'll experience
Significant mind-body benefits — in three steps.
The Complete Neuro-Reset works across the full autonomic system — not just mood, but sleep, cognition, immune response, and the physical experience of stress. Most patients report changes beginning within 24 hours of their session.
- — Who it's for
Is this for me?
The Neuroreset tends to resonate most with people who are already doing the work — therapy, exercise, reasonable sleep habits — but still feel like they're running at a higher baseline stress level than they should be.
It's also for people who've had a meaningful experience with ketamine before and want to go deeper — or who want to try ketamine for the first time in conditions designed to make it as effective as possible.
It is not a first step. It is not a first step. A Discovery Call is optional, but a pre-treatment evaluation is required before booking your session.
- You've tried antidepressants and they haven't been enough
Two or more medications with partial or no response. This addresses a different layer than medication reaches.
- You've processed the trauma — your body hasn't caught up
The mind can work through something while the nervous system stays in a state of readiness. This is designed for that gap.
- You're exhausted but can't fully rest — even when you sleep
A body that runs on high alert doesn't recover the way it should. The exhaustion is real, and it has a physical explanation.
- You want to go deeper with ketamine than you have before
People who've had a ketamine experience and felt limited by the noise in their nervous system often describe the Neuro-Reset as what they were looking for the first time.
Still unsure? That's exactly what the Discovery Call is for. It's a conversation — not a sales pitch. If the Neuro-Reset isn't the right fit, we'll tell you that directly and talk through what might be.
- — Your visit
What to expect on the day.
The Complete Neuro-Reset is a single visit of approximately three to four hours. Here's exactly what happens from the moment you arrive.
01
Arrival & preparation
Your care team reviews your health history, confirms your readiness, and answers any remaining questions.
~30 min
02
Stellate Ganglion Block + Vagus Nerve Hydrodissection
Administered by a board-certified physician using ultrasound guidance. You are awake and comfortable. Effects begin within minutes.
~20 min + rest
03
Ketamine therapy
Once the SGB and VNH have taken effect, your ketamine session begins in a private treatment room.
~60–90 min
03
Recovery
A quiet recovery period before you leave. We recommend scheduling session with your existing therapist within 48–72 hours to support the neuroplasticity window.
~30 min
- — Questions
Everything you want to know before you book.
Answers to what patients ask most before their first Complete Neuro-Reset session.
Ready to find out if Complete Neuroreset is right for you?
Our intake team responds within one business day. Discovery calls are free, confidential, and without obligation.
What exactly is the Complete Neuro-Reset?
The Complete Neuro-Reset is Hudson Mind’s multi-modal protocol combining stellate ganglion block, vagus nerve reset, and IV ketamine therapy — administered in sequence to maximize therapeutic effect. Each treatment builds on the last: the stellate ganglion block calms a hyperactive sympathetic nervous system, the vagus nerve hydrodissection restores parasympathetic balance, and IV ketamine — delivered to a now-settled nervous system — supports neuroplasticity and deeper therapeutic benefit. Designed for patients with complex or co-occurring conditions such as treatment-resistant depression alongside PTSD, with personalized aftercare support through follow-up.
Why does the sequence matter — why not just do ketamine alone?
How long does the session take?
Plan for approximately three to four hours total — including preparation, the stellate ganglion block, a rest period, the ketamine session, and recovery time before you leave. You should clear the remainder of your day.
What does it feel like?
The stellate ganglion block typically produces warmth and a sense of heaviness or flushing on one side of the face and neck, which fades within an hour. Some patients notice a shift in their baseline tension almost immediately. The ketamine session produces a dissociative, dream-like state — patients describe it as deeply relaxing, visually unusual, and emotionally open. You remain in a reclined position with monitoring throughout. Most patients describe feeling clearheaded and calm within a few hours of completing the session.
How do I prepare for my session?
Fast for at least four hours before the session. Avoid alcohol for 24 hours before. Wear comfortable, loose-fitting clothing. If you typically drive, arrange a ride home — you cannot drive after ketamine therapy, though you are safe to take public transportation. Clear your schedule for the remainder of the day. Your care team will send full preparation instructions when you book, and a pre-treatment evaluation call is required before your session date.
Do I need a referral?
No referral is required. Start with a free Discovery Call — our team will discuss your situation and determine whether the Complete Neuro-Reset is appropriate. A pre-treatment evaluation with one of our psychiatrists is required before booking your session date. If the Neuroreset isn’t the right fit, we’ll tell you honestly and discuss alternatives.
Can I take my current medications before the session?
This depends on the medication. Most antidepressants are fine to continue. Certain medications — including benzodiazepines, MAOIs, and some blood pressure medications — may need to be paused or adjusted. Your psychiatrist will review your full medication list during the pre-treatment evaluation and provide specific instructions. Do not adjust or stop any medication before consulting our team.
Should someone come with me?
If you typically drive, yes. A responsible adult must be available to take you home — you cannot drive after ketamine therapy. They do not need to stay during the session, but should be reachable and available to pick you up when your session ends. We can provide an estimated pickup time when you arrive. You are also safe to take a cab or public transportation home.
What are the side effects?
The stellate ganglion block may cause temporary effects on the side of the injection: a drooping eyelid (Horner’s syndrome), hoarseness, a feeling of warmth, or difficulty swallowing — all of which are expected and resolve within a few hours. Ketamine may produce mild dissociation, nausea, dizziness, or elevated heart rate during the infusion, which resolves quickly. You are monitored throughout the entire session by our clinical team.
Who is not a good candidate for the Complete Neuro-Reset?
The Complete Neuro-Reset is not appropriate for patients with active psychosis, uncontrolled hypertension, certain cardiovascular conditions, active substance use disorder, or those who are pregnant. Your pre-treatment evaluation screens for all contraindications. If you are not a candidate, we will tell you clearly and discuss alternative treatments at Hudson Mind that may be appropriate.
Is the Complete Neuro-Reset covered by insurance?
The Complete Neuro-Reset is currently a self-pay protocol. The individual treatments — stellate ganglion block and ketamine therapy — are not typically covered by insurance as standalone procedures. Hudson Mind provides full pricing transparency before any commitment. The pre-treatment psychiatric evaluation may be billable to insurance depending on your plan.Contact mind@hudson.health or view the pricing section of our website for current pricing.
Where is Hudson Mind located?
Hudson Mind is at 281 Broadway, Floor 2, New York, NY 10007 in Lower Manhattan. We are steps from the 4/5/6, A/C/E, J/Z, R/W, and 2/3 subway lines — accessible from all five boroughs and Northern New Jersey. Questions? Call or text (646) 906-8703 or email mind@hudson.health.
You've been managing.
This is something different.
Start with a free Discovery Call — a real conversation about your situation, with no pressure and no commitment. If the Neuroreset is right for you, we'll tell you exactly what comes next. If it isn't, we'll be honest about that too.
